Moyamoya disease-associated protein mysterin/RNF213 is a novel AAA+ ATPase, which dynamically changes its oligomeric state

Moyamoya disease is an idiopathic human cerebrovascular disorder that is characterized by progressive stenosis and abnormal collateral vessels. We recently identified mysterin/RNF213 as its first susceptibility gene, which encodes a 591-kDa protein containing enzymatically active P-loop ATPase and u...

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Hlavní autoři: Morito, Daisuke, Nishikawa, Kouki, Hoseki, Jun, Kitamura, Akira, Kotani, Yuri, Kiso, Kazumi, Kinjo, Masataka, Fujiyoshi, Yoshinori, Nagata, Kazuhiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963067/
https://ncbi.nlm.nih.gov/pubmed/24658080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04442
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