Biochemical and Functional Characterization of RNF213 (Mysterin) R4810K, a Susceptibility Mutation of Moyamoya Disease, in Angiogenesis In Vitro and In Vivo

BACKGROUND: P.R4810K of RNF213 (mysterin: rs112735431), which is an AAA(+) ATPase, is the susceptibility polymorphism for moyamoya disease (MMD) in East Asians. However, the role of RNF213 R4810K in the etiology of MMD is unknown. METHODS AND RESULTS: To clarify the role of RNF213 in known angiogeni...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Kobayashi, Hatasu, Matsuda, Yoshiko, Hitomi, Toshiaki, Okuda, Hiroko, Shioi, Hirotomo, Matsuda, Tetsuya, Imai, Hirohiko, Sone, Masakatsu, Taura, Daisuke, Harada, Kouji H, Habu, Toshiyuki, Takagi, Yasushi, Miyamoto, Susumu, Koizumi, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608092/
https://ncbi.nlm.nih.gov/pubmed/26126547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002146
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados