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Biodistribution and Clearance of Small Molecule Hapten Chelates for Pretargeted Radioimmunotherapy
PURPOSE: The favorable pharmacokinetics and clinical safety profile of metal-chelated 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA) suggests that it might be an ideal hapten for pretargeted radioimmunotherapy. In an effort to minimize hapten retention in normal tissues and determin...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962775/ https://ncbi.nlm.nih.gov/pubmed/20533093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-010-0353-6 |
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