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Polymorphism and resolution of oncogene promoter quadruplex-forming sequences

We report the separation of several quadruplex species formed by ten promoter sequences by Size Exclusion Chromatography (SEC). Modification at the 5’ or 3’ ends or in loop regions of quadruplex forming sequences has become the standard technique for dealing with quadruplex polymorphism. However, co...

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書誌詳細
主要な著者: Miller, M. Clarke, Le, Huy T., Dean, William L., Holt, Patrick A., Chaires, Jonathan B., Trent, John O.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962748/
https://ncbi.nlm.nih.gov/pubmed/21938285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1ob05891f
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