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The Adherens Junction Protein Afadin is an Akt substrate that Regulates Breast Cancer Cell Migration
The PI 3-K and Akt signaling pathway regulates all phenotypes that contribute to progression of human cancers, including breast cancer. Akt mediates signal relay by phosphorylating numerous substrates, which are causally implicated in responses such as cell growth, survival, metabolic reprograming a...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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2013
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962723/ https://ncbi.nlm.nih.gov/pubmed/24269953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0398 |
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