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The Adherens Junction Protein Afadin is an Akt substrate that Regulates Breast Cancer Cell Migration

The PI 3-K and Akt signaling pathway regulates all phenotypes that contribute to progression of human cancers, including breast cancer. Akt mediates signal relay by phosphorylating numerous substrates, which are causally implicated in responses such as cell growth, survival, metabolic reprograming a...

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Main Authors: Elloul, Sivan, Kedrin, Dmitriy, Knoblauch, Nicholas W., Beck, Andrew H., Toker, Alex
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962723/
https://ncbi.nlm.nih.gov/pubmed/24269953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-13-0398
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