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Optimization of precursor synthesis, formulation and stability of 1′-[(18) F] fluoroethyl-β-d-lactose ([(18) F]FEL) for preclinical studies in detection of pancreatic cancer
INTRODUCTION: 1′-[(18) F]Fluoroethyl-β-d-lactose ([(18) F]FEL) is a new PET imaging agent for early detection of pancreatic cancer and hepatocellular carcinoma. We previously reported the syntheses of [(18) F]FEL using a bromo- and a tosyl- precursor, followed by an improved method using a nosyl-pre...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962678/ https://ncbi.nlm.nih.gov/pubmed/24508409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2014.01.002 |
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