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Removal of Inflammatory Ascites is Associated with Dynamic Modification of Local and Systemic Inflammation along with Prevention of Acute Lung Injury: In Vivo and In Silico Studies

BACKGROUND: Sepsis-induced inflammation in the gut/peritoneal compartment occurs early in sepsis, and can lead to acute lung injury (ALI). We have suggested that inflammatory ascites drives the pathogenesis of ALI, and that removal of ascites with an abdominal wound vacuum prevents ALI. We hypothesi...

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Main Authors: Emr, Bryanna, Sadowsky, David, Azhar, Nabil, Gatto, Louis A., An, Gary, Nieman, Gary, Vodovotz, Yoram
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962670/
https://ncbi.nlm.nih.gov/pubmed/24430553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000121
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