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Removal of Inflammatory Ascites is Associated with Dynamic Modification of Local and Systemic Inflammation along with Prevention of Acute Lung Injury: In Vivo and In Silico Studies

BACKGROUND: Sepsis-induced inflammation in the gut/peritoneal compartment occurs early in sepsis, and can lead to acute lung injury (ALI). We have suggested that inflammatory ascites drives the pathogenesis of ALI, and that removal of ascites with an abdominal wound vacuum prevents ALI. We hypothesi...

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Библиографические подробности
Главные авторы: Emr, Bryanna, Sadowsky, David, Azhar, Nabil, Gatto, Louis A., An, Gary, Nieman, Gary, Vodovotz, Yoram
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962670/
https://ncbi.nlm.nih.gov/pubmed/24430553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0000000000000121
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