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Novel role of aminopeptidase-A in angiotensin-(1–7) metabolism post myocardial infarction

Aminopeptidase-A (APA) is a less well-studied enzyme of the renin-angiotensin system. We propose that it is involved in cardiac angiotensin (ANG) metabolism and its pathologies. ANG-(1–7) can ameliorate remodeling after myocardial injury. The aims of this study are to 1) develop mass spectrometric (...

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Detalhes bibliográficos
Main Authors: Alghamri, Mahmoud S., Morris, Mariana, Meszaros, J. Gary, Elased, Khalid M., Grobe, Nadja
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962633/
https://ncbi.nlm.nih.gov/pubmed/24464749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00911.2013
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