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EGFR ligands exhibit functional differences in models of paracrine and autocrine signaling

Epidermal growth factor (EGF) family peptides are ligands for the EGF receptor (EGFR). Here, we elucidate functional differences among EGFR ligands and mechanisms underlying these distinctions. In 32D/EGFR myeloid and MCF10A breast cells, soluble amphiregulin (AR), transforming growth factor alpha (...

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Autors principals: Wilson, Kristy J., Mill, Christopher, Lambert, Sydney, Buchman, Jennifer, Wilson, Timothy R., Hernandez-Gordillo, Victor, Gallo, Richard M., Ades, Laura M.C., Settleman, Jeffrey, Riese, David J.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962550/
https://ncbi.nlm.nih.gov/pubmed/22260327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/08977194.2011.649918
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