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Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat.

Marked increases in intracellular calcium may play a role in mediating cellular dysfunction and death following central nervous system trauma, in part through the activation of the calcium-dependent neutral protease calpain. In this study, we evaluated the effect of the calpain inhibitor AK295 [Z-Le...

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Bibliografske podrobnosti
Main Authors: Saatman, K E, Murai, H, Bartus, R T, Smith, D H, Hayward, N J, Perri, B R, McIntosh, T K
Format: Artigo
Jezik:Inglês
Izdano: 1996
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC39625/
https://ncbi.nlm.nih.gov/pubmed/8622952
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