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Simplifying the complexity of resistance heterogeneity in metastasis

The main goal of treatment regimens for metastasis is to control growth rates, not eradicate all cancer cells. Mathematical models offer methodologies that incorporate high-throughput data with dynamic effects on net growth. The ideal approach would simplify, but not over-simplify, a complex problem...

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Detalhes bibliográficos
Main Authors: Lavi, Orit, Greene, James M., Levy, Doron, Gottesman, Michael M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962236/
https://ncbi.nlm.nih.gov/pubmed/24491979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2013.12.005
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