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Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells
Thrombin is the key serine protease of the coagulation cascade and a potent trigger of protease-activated receptor 1 (PAR1)-mediated platelet aggregation. In recent years, PAR1 has become an appealing target for anticoagulant therapies. However, the inhibitors that have been developed so far increas...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3962174/ https://ncbi.nlm.nih.gov/pubmed/24501219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-12-546036 |
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