Amphetamine and Methamphetamine Reduce Striatal Dopamine Transporter Function Without Concurrent Dopamine Transporter Relocalization

Amphetamine (AMPH) and methamphetamine (METH) alter dopamine (DA) transporter (DAT) function. In vitro heterologous cell line and synaptosome studies demonstrate AMPH-induced DAT internalization, implicating relocalization in reduced DAT uptake following drug exposure. However, few studies have eval...

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Bibliographic Details
Main Authors: German, Christopher L., Hanson, Glen R., Fleckenstein, Annette E.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962019/
https://ncbi.nlm.nih.gov/pubmed/22804716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07875.x
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