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Amphetamine and Methamphetamine Reduce Striatal Dopamine Transporter Function Without Concurrent Dopamine Transporter Relocalization

Amphetamine (AMPH) and methamphetamine (METH) alter dopamine (DA) transporter (DAT) function. In vitro heterologous cell line and synaptosome studies demonstrate AMPH-induced DAT internalization, implicating relocalization in reduced DAT uptake following drug exposure. However, few studies have eval...

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Bibliografische gegevens
Hoofdauteurs: German, Christopher L., Hanson, Glen R., Fleckenstein, Annette E.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3962019/
https://ncbi.nlm.nih.gov/pubmed/22804716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2012.07875.x
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