Lipoprotein activators stimulate Escherichia coli penicillin-binding proteins by different mechanisms

In Escherichia coli, the bifunctional penicillin-binding proteins (PBPs), PBP1A and PBP1B, play critical roles in the final stage of peptidoglycan (PG) biosynthesis. These synthetic enzymes each possess a PG glycosyltransferase (PGT) domain and a transpeptidase (TP) domain. Recent genetic experiment...

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Bibliographic Details
Main Authors: Lupoli, Tania J., Lebar, Matthew D., Markovski, Monica, Bernhardt, Thomas, Kahne, Daniel, Walker, Suzanne
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961711/
https://ncbi.nlm.nih.gov/pubmed/24341982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja410813j
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