Pleiotropic Effects of Cavin-1 Deficiency on Lipid Metabolism

Mice and humans lacking caveolae due to gene knock-out or inactivating mutations of cavin-1/PTRF have numerous pathologies including markedly aberrant fuel metabolism, lipodystrophy, and muscular dystrophy. We characterized the physiologic/metabolic profile of cavin-1 knock-out mice and determined t...

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Bibliographic Details
Main Authors: Ding, Shi-Ying, Lee, Mi-Jeong, Summer, Ross, Liu, Libin, Fried, Susan K., Pilch, Paul F.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961672/
https://ncbi.nlm.nih.gov/pubmed/24509860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546242
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