Interaction with the Bardet-Biedl Gene Product TRIM32/BBS11 Modifies the Half-life and Localization of Glis2/NPHP7

Although the two ciliopathies Bardet-Biedl syndrome and nephronophthisis share multiple clinical manifestations, the molecular basis for this overlap remains largely unknown. Both BBS11 and NPHP7 are unusual members of their respective gene families. Although BBS11/TRIM32 represents a RING finger E3...

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Autors principals: Ramachandran, Haribaskar, Schäfer, Tobias, Kim, Yunhee, Herfurth, Konstantin, Hoff, Sylvia, Lienkamp, Soeren S., Kramer-Zucker, Albrecht, Walz, Gerd
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
Matèries:
Molecular Bases of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961664/
https://ncbi.nlm.nih.gov/pubmed/24500717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534024
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