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Interaction with the Bardet-Biedl Gene Product TRIM32/BBS11 Modifies the Half-life and Localization of Glis2/NPHP7

Although the two ciliopathies Bardet-Biedl syndrome and nephronophthisis share multiple clinical manifestations, the molecular basis for this overlap remains largely unknown. Both BBS11 and NPHP7 are unusual members of their respective gene families. Although BBS11/TRIM32 represents a RING finger E3...

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Detalhes bibliográficos
Main Authors: Ramachandran, Haribaskar, Schäfer, Tobias, Kim, Yunhee, Herfurth, Konstantin, Hoff, Sylvia, Lienkamp, Soeren S., Kramer-Zucker, Albrecht, Walz, Gerd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961664/
https://ncbi.nlm.nih.gov/pubmed/24500717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534024
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