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Mathematical modeling of escape of HIV from cytotoxic T lymphocyte responses

Human immunodeficiency virus (HIV-1 or simply HIV) induces a persistent infection, which in the absence of treatment leads to AIDS and death in almost all infected individuals. HIV infection elicits a vigorous immune response starting about 2–3 weeks post infection that can lower the amount of virus...

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Main Authors: Ganusov, Vitaly V., Neher, Richard A., Perelson, Alan S.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961578/
https://ncbi.nlm.nih.gov/pubmed/24660019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1742-5468/2013/01/P01010
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