Alterations of Ca(2+) responsive proteins within cholinergic neurons in aging and AD

The molecular basis of selective neuronal vulnerability in Alzheimer ’s disease (AD) remains poorly understood. Using basal forebrain cholinergic neurons (BFCN) as a model and immunohistochemistry, we have demonstrated significant age-related loss of the calcium binding protein calbindin-D(28K) (CB)...

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Detalhes bibliográficos
Main Authors: Riascos, David, Nicholas, Alexander, Samaeekia, Ravand, Yukhnanov, Rustam, Mesulam, M.-Marsel, Bigio, Eileen H., Weintraub, Sandra, Guo, Ling, Geula, Changiz
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961506/
https://ncbi.nlm.nih.gov/pubmed/24461366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.12.017
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