Characterisation of Genetic Variation in ST8SIA2 and Its Interaction Region in NCAM1 in Patients with Bipolar Disorder

Alpha-2,8-sialyltransferase 2 (ST8SIA2) is an enzyme responsible for the transfer of polysialic acid (PSA) to glycoproteins, principally the neuronal cell adhesion molecule (NCAM1), and is involved in neuronal plasticity. Variants within ST8SIA2 have previously shown association with bipolar disorde...

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Détails bibliographiques
Auteurs principaux: Shaw, Alex D., Tiwari, Yash, Kaplan, Warren, Heath, Anna, Mitchell, Philip B., Schofield, Peter R., Fullerton, Janice M.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961385/
https://ncbi.nlm.nih.gov/pubmed/24651862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092556
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