Inflammation-Induced Acute Phase Response in Skeletal Muscle and Critical Illness Myopathy

OBJECTIVES: Systemic inflammation is a major risk factor for critical-illness myopathy (CIM) but its pathogenic role in muscle is uncertain. We observed that interleukin 6 (IL-6) and serum amyloid A1 (SAA1) expression was upregulated in muscle of critically ill patients. To test the relevance of the...

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Autors principals: Langhans, Claudia, Weber-Carstens, Steffen, Schmidt, Franziska, Hamati, Jida, Kny, Melanie, Zhu, Xiaoxi, Wollersheim, Tobias, Koch, Susanne, Krebs, Martin, Schulz, Herbert, Lodka, Doerte, Saar, Kathrin, Labeit, Siegfried, Spies, Claudia, Hubner, Norbert, Spranger, Joachim, Spuler, Simone, Boschmann, Michael, Dittmar, Gunnar, Butler-Browne, Gillian, Mouly, Vincent, Fielitz, Jens
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961297/
https://ncbi.nlm.nih.gov/pubmed/24651840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092048
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