טוען...
BxPC3 pancreatic cancer cells express a truncated Smad4 protein upon PI3K and mTOR inhibition
Smad4 is a critical regulator of transforming growth factor (TGF)-β signaling and is defective in numerous human cancers. In total, 30% of pancreatic cancers harbor a homozygous deletion of Smad4. The human pancreatic cancer cell line, BxPC3, has been reported to be Smad4-null due to a homozygous de...
שמור ב:
| Main Authors: | , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
D.A. Spandidos
2014
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3961292/ https://ncbi.nlm.nih.gov/pubmed/24944686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.1833 |
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