Genome-Wide Meta-Analysis of Homocysteine and Methionine Metabolism Identifies Five One Carbon Metabolism Loci and a Novel Association of ALDH1L1 with Ischemic Stroke

Circulating homocysteine levels (tHcy), a product of the folate one carbon metabolism pathway (FOCM) through the demethylation of methionine, are heritable and are associated with an increased risk of common diseases such as stroke, cardiovascular disease (CVD), cancer and dementia. The FOCM is the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Williams, Stephen R., Yang, Qiong, Chen, Fang, Liu, Xuan, Keene, Keith L., Jacques, Paul, Chen, Wei-Min, Weinstein, Galit, Hsu, Fang-Chi, Beiser, Alexa, Wang, Liewei, Bookman, Ebony, Doheny, Kimberly F., Wolf, Philip A., Zilka, Michelle, Selhub, Jacob, Nelson, Sarah, Gogarten, Stephanie M., Worrall, Bradford B., Seshadri, Sudha, Sale, Michèle M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961178/
https://ncbi.nlm.nih.gov/pubmed/24651765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004214
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados