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Sugar and Chromosome Stability: Clastogenic Effects of Sugars in Vitamin B6-Deficient Cells

Pyridoxal 5′-phosphate (PLP), the active form of vitamin B6, has been implicated in preventing human pathologies, such as diabetes and cancer. However, the mechanisms underlying the beneficial effects of PLP are still unclear. Using Drosophila as a model system, we show that PLP deficiency, caused e...

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Главные авторы: Marzio, Antonio, Merigliano, Chiara, Gatti, Maurizio, Vernì, Fiammetta
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961173/
https://ncbi.nlm.nih.gov/pubmed/24651653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004199
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