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Asymmetry in Family History Implicates Nonstandard Genetic Mechanisms: Application to the Genetics of Breast Cancer

Genome-wide association studies typically target inherited autosomal variants, but less studied genetic mechanisms can play a role in complex disease. Sex-linked variants aside, three genetic phenomena can induce differential risk in maternal versus paternal lineages of affected individuals: 1. mate...

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Detalhes bibliográficos
Main Authors: Weinberg, Clarice R., Shi, Min, DeRoo, Lisa A., Taylor, Jack A., Sandler, Dale P., Umbach, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961172/
https://ncbi.nlm.nih.gov/pubmed/24651610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004174
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