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Asymmetry in family history implicates nonstandard genetic mechanisms: application to the genetics of breast cancer.
Genome-wide association studies typically target inherited autosomal variants, but less studied genetic mechanisms can play a role in complex disease. Sex-linked variants aside, three genetic phenomena can induce differential risk in maternal versus paternal lineages of affected individuals: 1. mate...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2014-03-01
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Colecção: | PLoS Genetics |
Acesso em linha: | http://europepmc.org/articles/PMC3961172?pdf=render |
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