Probabilistic Approach to Predicting Substrate Specificity of Methyltransferases

We present a general probabilistic framework for predicting the substrate specificity of enzymes. We designed this approach to be easily applicable to different organisms and enzymes. Therefore, our predictive models do not rely on species-specific properties and use mostly sequence-derived data. Ma...

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Detalhes bibliográficos
Main Authors: Szczepińska, Teresa, Kutner, Jan, Kopczyński, Michał, Pawłowski, Krzysztof, Dziembowski, Andrzej, Kudlicki, Andrzej, Ginalski, Krzysztof, Rowicka, Maga
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961171/
https://ncbi.nlm.nih.gov/pubmed/24651469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003514
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