Probabilistic Approach to Predicting Substrate Specificity of Methyltransferases

We present a general probabilistic framework for predicting the substrate specificity of enzymes. We designed this approach to be easily applicable to different organisms and enzymes. Therefore, our predictive models do not rely on species-specific properties and use mostly sequence-derived data. Ma...

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Bibliografski detalji
Glavni autori: Szczepińska, Teresa, Kutner, Jan, Kopczyński, Michał, Pawłowski, Krzysztof, Dziembowski, Andrzej, Kudlicki, Andrzej, Ginalski, Krzysztof, Rowicka, Maga
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3961171/
https://ncbi.nlm.nih.gov/pubmed/24651469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003514
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