Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors.
Adenovirus (Ad) vectors have been extensively used to deliver recombinant genes to a great variety of cell types in vitro and in vivo. Ad-based vectors are available that replace the Ad early region 1 (E1) with recombinant foreign genes. The resultant E1-deleted vectors can then be propagated on 293...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39611/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622940/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3352 |
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