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Smad3 Binds Scleraxis and Mohawk and Regulates Tendon Development

TGFβ plays a critical role in tendon formation and healing. While its downstream effector Smad3 has been implicated in the healing process, little is known about the role of Smad3 in normal tendon development or tenocyte gene expression. Using mice deficient in Smad3 (Smad3(–/–)), we show that Smad3...

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Detalhes bibliográficos
Main Authors: Berthet, Ellora, Chen, Carol, Butcher, Kristin, Schneider, Richard A., Alliston, Tamara, Amirtharajah, Mohana
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960924/
https://ncbi.nlm.nih.gov/pubmed/23653374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.22382
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