Effect of Prenatal Hypoxia in Transgenic Mouse Models of Preeclampsia and Fetal Growth Restriction

Mice lacking endothelial nitric oxide synthase (eNOS(−) (/−)) or catechol-O-methyl transferase (COMT(−/−)) exhibit a preeclampsia-like phenotype and fetal growth restriction. We hypothesized that a hypoxic insult would result in a more severe phenotype. Pregnant eNOS(−/−), COMT(−/−) and control (C57...

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Bibliographic Details
Main Authors: Rueda-Clausen, C. F., Stanley, J. L., Thambiraj, D. F., Poudel, R., Davidge, S. T., Baker, P. N.
Format: Artigo
Language:Inglês
Published: SAGE Publications 2014
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960835/
https://ncbi.nlm.nih.gov/pubmed/24084523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719113503401
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