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Sildenafil Therapy Normalizes the Aberrant Metabolomic Profile in the Comt(−/−) Mouse Model of Preeclampsia/Fetal Growth Restriction

Preeclampsia (PE) and fetal growth restriction (FGR) are serious complications of pregnancy, associated with greatly increased risk of maternal and perinatal morbidity and mortality. These complications are difficult to diagnose and no curative treatments are available. We hypothesized that the meta...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Stanley, Joanna L., Sulek, Karolina, Andersson, Irene J., Davidge, Sandra T., Kenny, Louise C., Sibley, Colin P., Mandal, Rupasri, Wishart, David S., Broadhurst, David I., Baker, Philip N.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4678899/
https://ncbi.nlm.nih.gov/pubmed/26667607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep18241
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