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mGluR5 Upregulation Increases Excitability of Hypothalamic Presympathetic Neurons through NMDA Receptor Trafficking in Spontaneously Hypertensive Rats

The hypothalamic paraventricular nucleus (PVN) is critically involved in elevated sympathetic output and the development of hypertension. However, changes in group I metabotropic glutamate receptors (mGluR1 and mGluR5) and their relevance to the hyperactivity of PVN presympathetic neurons in hyperte...

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Autori principali: Pachuau, Judith, Lee, Hae-Ahm
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960469/
https://ncbi.nlm.nih.gov/pubmed/24647951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4295-13.2014
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