CaMKII Regulates Synaptic NMDA Receptor Activity of Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension

NMDAR activity in the hypothalamic paraventricular nucleus (PVN) is increased and critically involved in heightened sympathetic vasomotor tone in hypertension. Calcium/calmodulin-dependent protein kinase II (CaMKII) binds to and modulates NMDAR activity. In this study, we determined the role of CaMK...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Li, De-Pei, Zhou, Jing-Jing, Zhang, Jixiang, Pan, Hui-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5666588/
https://ncbi.nlm.nih.gov/pubmed/28972129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2141-17.2017
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