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GNG2 inhibits invasion of human malignant melanoma cells with decreased FAK activity

It is well known that heterotrimeric G protein is composed of a Gα-subunit and a Gβγ-dimer and promotes cancer characteristics. Our recent study showed reduced G protein γ2 subunit (Gng2/GNG2) expression levels in malignant melanoma cells compared with those in benign melanocytic cells in both mice...

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Bibliografiske detaljer
Main Authors: Yajima, Ichiro, Kumasaka, Mayuko Y, Yamanoshita, Osamu, Zou, Cunchao, Li, Xiang, Ohgami, Nobutaka, Kato, Masashi
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960455/
https://ncbi.nlm.nih.gov/pubmed/24660107
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