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Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends

Mechanistic target of rapamycin (mTOR) regulates cell growth, metabolism and aging in response to nutrients, cellular energy stage and growth factors. mTOR is frequently up-regulated in cancer including hepatocellular carcinoma (HCC) and is associated with bad prognosis, poorly differentiated tumors...

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Dettagli Bibliografici
Autori principali: Matter, Matthias S., Decaens, Thomas, Andersen, Jesper B., Thorgeirsson, Snorri S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960348/
https://ncbi.nlm.nih.gov/pubmed/24308993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.11.031
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