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Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends
Mechanistic target of rapamycin (mTOR) regulates cell growth, metabolism and aging in response to nutrients, cellular energy stage and growth factors. mTOR is frequently up-regulated in cancer including hepatocellular carcinoma (HCC) and is associated with bad prognosis, poorly differentiated tumors...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3960348/ https://ncbi.nlm.nih.gov/pubmed/24308993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.11.031 |
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