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Melatonin Combined with Endoplasmic Reticulum Stress Induces Cell Death via the PI3K/Akt/mTOR Pathway in B16F10 Melanoma Cells

This study investigated B16F10 melanoma cell death induced by melatonin combined with endoplasmic reticulum (ER) stress through the PI3K/Akt/mTOR pathway. Cell viability was significantly decreased after treatment with melatonin combined with ER stress from thapsigargin or tunicamycin compared to no...

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Detalhes bibliográficos
Main Authors: Kim, Han Sung, Kim, Tack-Joong, Yoo, Yeong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960269/
https://ncbi.nlm.nih.gov/pubmed/24647338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092627
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