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Combined Fluid Shear Stress and Melatonin Enhances the ERK/Akt/mTOR Signal in Cilia-Less MC3T3-E1 Preosteoblast Cells

We investigated whether combined fluid shear stress (FSS) and melatonin stimulated signal transduction in cilia-less MC3T3-E1 preosteoblast cells. MC3T3-E1 cells were treated with chloral hydrate or nocodazole, and mechanotransduction sensor primary cilia were removed. p-extracellular signal–regulat...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Chi Hyun, Jeung, Eui-Bae, Yoo, Yeong-Min
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6213863/
https://ncbi.nlm.nih.gov/pubmed/30261648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19102929
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