4-Hydroxylation of estrogens as marker of human mammary tumors.
Estrogen is a known risk factor in human breast cancer. In rodent models, estradiol has been shown to induce tumors in those tissues in which this hormone is predominantly converted to the catechol metabolite 4-hydroxyestradiol by a specific 4-hydroxylase enzyme, whereas tumors fail to develop in or...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3294 |
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