4-Hydroxylation of estrogens as marker of human mammary tumors.
Estrogen is a known risk factor in human breast cancer. In rodent models, estradiol has been shown to induce tumors in those tissues in which this hormone is predominantly converted to the catechol metabolite 4-hydroxyestradiol by a specific 4-hydroxylase enzyme, whereas tumors fail to develop in or...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1996
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39600/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622931/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3294 |
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