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Calcium binding is essential for plastin 3 function in Smn-deficient motoneurons
The actin-binding and bundling protein, plastin 3 (PLS3), was identified as a protective modifier of spinal muscular atrophy (SMA) in some patient populations and as a disease modifier in animal models of SMA. How it functions in this process, however, is not known. Because PLS3 is an actin-binding/...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959813/ https://ncbi.nlm.nih.gov/pubmed/24271012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt595 |
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