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Human mitochondrial DNA: roles of inherited and somatic mutations
Mutations in the human mitochondrial genome are known to cause an array of diverse disorders, most of which are maternally inherited, and all of which are associated with defects in oxidative energy metabolism. It is now emerging that somatic mutations in mitochondrial DNA (mtDNA) are also linked to...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959762/ https://ncbi.nlm.nih.gov/pubmed/23154810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg3275 |
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