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Deletion of Krüppel‐Like Factor 4 in Endothelial and Hematopoietic Cells Enhances Neointimal Formation Following Vascular Injury

BACKGROUND: Krüppel‐like factor 4 (Klf4) is involved in a variety of cellular functions by activating or repressing the transcription of multiple genes. Results of previous studies showed that tamoxifen‐inducible global deletion of the Klf4 gene in mice accelerated neointimal formation following vas...

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Autors principals: Yoshida, Tadashi, Yamashita, Maho, Horimai, Chihiro, Hayashi, Matsuhiko
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959705/
https://ncbi.nlm.nih.gov/pubmed/24470523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000622
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