FoxO6 Integrates Insulin Signaling With MTP for Regulating VLDL Production in the Liver

Excessive production of triglyceride-rich very low-density lipoproteins (VLDL-TG) contributes to hypertriglyceridemia in obesity and type 2 diabetes. To understand the underlying mechanism, we studied hepatic regulation of VLDL-TG production by (forkhead box O6) FoxO6, a forkhead transcription facto...

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Autors principals: Kim, Dae Hyun, Zhang, Ting, Lee, Sojin, Calabuig-Navarro, Virtu, Yamauchi, Jun, Piccirillo, Ann, Fan, Yong, Uppala, Radha, Goetzman, Eric, Dong, H. Henry
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2014
Matèries:
Diabetes-Insulin-Glucagon-Gastrointestinal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959596/
https://ncbi.nlm.nih.gov/pubmed/24437489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-1856
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