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Cell-interdependent cisplatin killing by Ku/DNA-dependent protein kinase signaling transduced through gap junctions
Cisplatin is one of the most widely used cancer chemotherapy agents, but its mechanism of action is not fully understood. Current models suggest that cell killing by cisplatin occurs in a cell-autonomous manner by means of formation of platinum-DNA adducts that, if not removed by DNA repair, block t...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395935/ https://ncbi.nlm.nih.gov/pubmed/15069205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400051101 |
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