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Essential role of CD91 in re-presentation of gp96-chaperoned peptides

Heat shock proteins (HSPs) such as gp96 are released from cells as a result of necrotic cell death. The ability of endogenous HSP–peptide complexes to elicit antigen-specific T cells requires representation of the chaperoned peptides by antigen-presenting cells. Re-presentation requires the uptake o...

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Detalhes bibliográficos
Main Authors: Binder, Robert J., Srivastava, Pramod K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395934/
https://ncbi.nlm.nih.gov/pubmed/15073331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308180101
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