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High efficiency CD91- and LOX-1-mediated re-presentation of gp96-chaperoned peptides by MHC II molecules

Exogenous antigens enter antigen-presenting cells through non-specific mechanisms and are presented by the MHC II molecules. We show here that antigens chaperoned by the heat shock protein gp96 enter dendritic cells and B cells through a specific, CD91- and LOX-1-mediated mechanism, and are presente...

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Detalhes bibliográficos
Main Authors: Matsutake, Toyoshi, Sawamura, Tatsuya, Srivastava, Pramod K.
Formato: Artigo
Idioma:Inglês
Publicado em: Academy of Cancer Immunology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964010/
https://ncbi.nlm.nih.gov/pubmed/20672796
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