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Power of Family-Based Association Designs To Detect Rare Variants in Large Pedigrees Using Imputed Genotypes
Recently, the “Common Disease-Multiple Rare Variants” hypothesis has received much attention, especially with current availability of next generation sequencing. Family-based designs are well suited for discovery of rare variants, with large and carefully selected pedigrees enriching for multiple co...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3959172/ https://ncbi.nlm.nih.gov/pubmed/24243664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21776 |
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